Clinical Trials Database

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https://www.clinicaltrials.gov/ct2/home

Search the database of privately and publicly funded clinical studies in US and around the world: ClinicalTrials.gov is a centralized registry and results database for clinical studies involving human participants, managed by the National Institutes of Health. It provides a standardized repository for trial protocols, recruitment status, eligibility criteria, and summary results, including primary outcome measures and adverse event data.

The platform ensures transparency in the clinical research ecosystem by aggregating data from both privately and publicly funded trials, facilitating the tracking of medical research progress across diverse therapeutic areas and global jurisdictions.

Easy access and RSS available from searches.

Professionals in science and medicine apply this data to drive strategic decision-making and regulatory alignment:

Science and Innovation: Researchers perform competitive intelligence and meta-analyses of trial outcomes to identify therapeutic gaps, benchmark candidate efficacy against competitors, and refine R&D pipelines.
Quality and Manufacturing: Quality specialists monitor safety signals and clinical performance metrics to inform post-market surveillance and ensure that manufacturing process changes do not negatively impact clinical outcomes.
Engineering: Biomedical engineers leverage clinical benchmarks to define technical specifications and validation protocols for medical devices, ensuring hardware and software requirements align with clinical endpoints.

Disciplines: Clinical research, Medicine, Pharmaceutical development, Regulatory affairs, Biostatistics, Public health.

Free alternative to EU Clinical Trials Register, WHO ICTRP, Cortellis.

ClinicalTrials.gov compared with EU Clinical Trials Register, WHO ICTRP and Cortellis
ClinicalTrials.gov	EU Clinical Trials Register	WHO ICTRP	Cortellis
Scope: A registry and results database for clinical studies. The WHO lists it among the data providers that feed the ICTRP Search Portal.	Scope: Limited to interventional medicine trials: adult Phase II to IV trials with EU/EEA investigator sites, and paediatric trials that meet set criteria. Trials must have started after 1 May 2004. Observational, surgical, device and psychotherapy trials are excluded.	Scope: A single search portal over records from 20 listed data providers, including ClinicalTrials.gov, the EU Clinical Trials Register and the EMA Clinical Trials Information System. It also groups records that describe the same trial.	Scope: A commercial platform from Clarivate. A 2020 vendor announcement cited more than 380,000 trials, over 2,900 diseases and data from more than 35 clinical trial registries, plus literature citations, conference presentations and press releases.
Results data: Basic results are shown in four modules: participant flow, baseline characteristics, outcome measures with statistical analyses, and adverse events. Sponsors or principal investigators submit them, and the tables carry no conclusions or individual patient data.	Results data: Summary results cover trial information, subject disposition, baseline characteristics, endpoints, adverse events and summary attachments. Sponsors enter the data and publish it once validated. Older paediatric trials under an EU marketing authorisation get only a reduced set of fields.
	Access and export: The search tool is free. Downloads are limited to 20 results per request, delivered as a plain text file.	Access and export: The portal documentation lists record downloads, a WHO data set, a Web Service and a Crawling Service, but the main portal page gives no details on cost or update frequency.
Typical use: Researchers use it for competitive intelligence and meta-analysis of trial outcomes. Quality staff screen it for safety signals, and biomedical engineers take clinical benchmarks from it to set device validation requirements.	Typical use: Suited to checking medicinal product trials run in the EU/EEA. Because device and observational studies are excluded, it cannot cover those.	Typical use: Suited to one search across many national and regional registries when the same trial may be registered more than once.	Typical use: Aimed at clinical development and clinical operations teams for trial design, site selection and patient recruitment planning.

Topics covered: Clinical Trials, Clinical Studies, Registry, Results Database, Human Participants, National Institutes of Health, Trial Protocols, Recruitment Status, Eligibility Criteria, Adverse Event Data, Transparency, Medical Research, Therapeutic Areas, Regulatory Alignment, Competitive Intelligence, Meta-Analyses, Quality Surveillance, Biomedical EngineeringISO 14155, ICH E6 (R2), GCP (Good Clinical Practice), FDA 21 CFR Part 312, and ISO 9001..