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Neural Engineering: Bridging Brain and External World

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Neural engineering is a field where neuroscience meets engineering. It aims to create technologies that communicate or improve brain function. By combining biology, computer science, and electrical engineering, it allows us to connect with the brain. This helps in finding new ways to diagnose and treat brain issues.

Sectors like brain devices and brain-computer interfaces are growing fast. This growth comes from more older people and newer, easier medical procedures. The University of Illinois Urbana-Champaign offers an online talk for new students. It covers Bioengineering, Neural Engineering, and Computer Science + Bioengineering. The talk highlights how brain technology and interaction are changing healthcare.

Key Takeaways

  • Neural engineering merges neuroscience and engineering to develop brain-enhancing technologies.
  • Increasing demand for neurological devices and minimally invasive procedures fuels industry growth.
  • The University of Illinois Urbana-Champaign emphasizes neural engineering in its multidisciplinary programs.
  • Brain-computer interfaces are at the forefront of neural engineering advancements.
  • Neural systems play a significant role in the future of medical diagnostics and treatments.

Introduction to Neural Engineering

Neural engineering is at the cutting edge of biomedical breakthroughs. It combines neuroscience and engineering. The goal is to interface with the nervous system, improving human abilities and fixing neurological issues. Knowing the basics of neural engineering is key to understanding its big effect on medicine and tech.

The human brain is complex, weighing about three pounds and hosting around 86 billion neurons, plus many glial cells. This network is crucial for cognition, which neural engineering seeks to enhance. A good intro to neuroengineering makes its groundbreaking principles clear.

The adult human brain contains about 86 billion neurons and trillions of synapses, making it a focal point of study in neural engineering.

Experts in neural engineering are also looking for ways to treat brain issues like stroke, spinal injury, or epilepsy. They aim to boost brain functions such as memory and attention. But, their work brings up serious questions about privacy, ethics, and the effects on society.

The Foundations of Neural Engineering

The field of neural engineering is fascinating. It links our nervous system with artificial devices. It leans on neural coding, synaptic plasticity, and brain-computer interfaces (BCIs).

Neural Coding

Neural coding is about how neurons use electrical activity to process information. It’s vital for understanding how the brain speaks and processes signals. Researchers have discovered how different patterns are linked to sensations or actions.

This knowledge is essential for advancing BCI technology. It helps in making neural prosthetics more effective.

Synaptic Plasticity

Synaptic plasticity lets synapses change their strength based on activity. It is key to learning and memory. It lets our brain circuits get better over time.

In neural engineering, this concept helps improve artificial networks. It also makes neural devices work better with our bodies.

Brain-Computer Interfaces (BCIs)

brain-computer interfaces

BCIs are amazing tools that connect our brains directly with devices. They do this by turning brain signals into commands. This allows people to control things like computers or prosthetics with their minds.

This technology is a game-changer for people who can’t move easily. It also opens up new ways to enhance human abilities.

Neural engineering mixes knowledge from many areas like computational neuroscience and electrical engineering. Our growing know-how in neural coding, synaptic plasticity, and BCI technology lets us create new bridges. These bridges connect our brains with the world of devices.

Field Focus Examples
Neural Coding Information representation in neurons Deciphering sensory and motor signals
Synaptic Plasticity Adaptive changes in synapse strength Learning and memory
Brain-Computer Interfaces (BCIs) Direct brain-device communication Controlling prosthetics, assistive technologies

Brain-Computer Interfaces: Direct Communication with the Brain

Brain-Computer Interfaces, or BCIs, have changed how we think about the brain talking to machines. Now, people can control computers or artificial limbs just by using their brain waves. These amazing tools are divided into three types of brain-computer interfaces: noninvasive, invasive, and minimally invasive BCIs.

Noninvasive BCIs

Noninvasive BCIs work without surgery. They use special sensors on the outside to pick up brain signals. The most widely used technique is EEG, which records the brain’s electric vibes from the scalp. Hans Berger made a big leap in this field 80 years ago with his study of the alpha rhythm.

Since then, inventions like the P300 speller have emerged. It lets users pick letters on a screen just by thinking. Analyzing the brain’s rhythm and response patterns plays a big role in making these technologies work.

Invasive BCIs

Invasive BCIs require putting electrodes right into the brain. This method provides clearer signals but comes with risks. By training the brain, researchers have used this tech to give new abilities to those with serious physical limitations. Since the 1970s, we’ve seen major advances, including using brain signals to operate gadgets.

Minimally Invasive BCIs

Minimally invasive BCIs are less harsh than fully invasive ones but offer better signals than noninvasive types. They use advanced techniques to place devices inside the brain with less risk. With these tools, people can do things like use a computer, send emails, or move robotic arms just by thinking.

Type of BCI Methods/Tools Advantages Disadvantages
Noninvasive EEG Ease of acquisition, no surgery Lower signal clarity
Invasive Microelectrodes, ECoG High signal clarity Requires surgery, potential risks
Minimally Invasive Stereotactic depth macroelectrodes, intracortical microarrays Balance between clarity and invasiveness Less established than other methods

Neurostimulation Technologies

Neurostimulation technologies have changed how we treat neurological issues. They bring new options for treatment and research. Among these, Deep Brain Stimulation (DBS) and Transcranial Focused Ultrasound (tFUS) stand out. They use new ways to adjust brain activity and ease symptoms of various diseases.

Deep Brain Stimulation (DBS)

DBS technology works by placing electrodes in the brain. These help control abnormal brain activity. It’s helpful for Parkinson’s disease and essential tremor. DBS targets treatment accurately, reducing bad symptoms and bettering life quality.

DBS technology

Wireless and battery-free implants introduced on April 27, 2023, are big advancements. They offer constant brain activity regulation without regular surgeries or changing batteries. This improves patient comfort and the device’s life.

Transcranial Focused Ultrasound (tFUS)

tFUS is a big step in noninvasive neurostimulation. It targets brain areas with ultrasound waves. This doesn’t require surgery. It’s a good choice for patients who prefer not to have invasive procedures.

tFUS doesn’t just adjust brain circuits. It can treat many neurological issues. For example, it works for psychiatric disorders, chronic pain, and delivering drugs directly to the brain.

DBS and tFUS offer two unique ways to help advance neurostimulation methods. As the demand for these devices grows, seen from 2013 to 2024, they continue to improve treatment for brain conditions. They offer new hope to millions suffering from these complex issues.

Technology Characteristics Applications
DBS Technology Implanted electrodes, precise electrical stimulation Parkinson’s disease, essential tremor, dystonia
tFUS Applications Noninvasive, focused ultrasound waves Chronic pain, psychiatric disorders, drug delivery

Applications of Neural Engineering in Medicine

Medical applications of neural engineering are changing how we understand and treat brain disorders. These applications combine advanced technology and medical science. They bring new ways to diagnose and treat brain problems, improving patient outcomes.

Treatment of Neurological Disorders

Neuromodulation is a key area in neural engineering. Neuromodulator devices help manage symptoms of Parkinson’s disease, dystonia, tremors, Tourette’s, chronic pain, OCD, severe depression, and epilepsy. Treating brain disorders with techniques like deep brain stimulation (DBS) and electrical stimulation can change neural activity. This helps restore normal brain functions.

Research is also working on better electrode arrays and data systems. This allows for accurate brain area recordings and stimulations. Such advances are vital for treatments that aim to bring back motor skills and other brain functions.

Advanced Neuroimaging Techniques

Neuroimaging techniques have vastly improved our ability to study brain activity. New imaging tech provides a clear picture of the brain. This helps doctors diagnose and assess different brain conditions. Using these methods alongside neural engineering lets experts collect detailed data. This data is essential for personalized treatments.

High-quality neuroimaging is key to understanding the brain’s structure. It also helps monitor treatment progress. This level of detail in neuroimaging advancements is crucial for managing brain disorders. It leads to new treatment methods.

Neural Engineering Technique Application Impact
Deep Brain Stimulation (DBS) Treating Parkinson’s disease, tremors, dystonia Alters neural activity to alleviate symptoms
Electrical Stimulation Restoration of motor functions, bladder control Stimulates neural pathways to regain function
Neuroimaging Techniques Brain mapping, diagnostic evaluation High-resolution data for detailed brain analysis

These outstanding techniques show the strong potential of neural engineering in medicine. They are key to diagnosing, treating, and understanding complex brain disorders.

Wearable Neural Engineering Devices

The creation of wearable neural engineering gadgets has changed how we monitor the brain. Now, devices like *EEG headsets* and smart glasses let us see brain activity as it happens. They catch the brain’s electrical signals in a way that doesn’t hurt the person wearing them. This is key for medical and everyday uses.

*EEG headsets* give us a 3D view of brain activity. This is big because they don’t have to cut into the person. So, many people, including researchers and those curious about brain health, use them. They can look at brain activity without any surgery, setting them apart in the world of brain-computer links (BCIs).

wearable neural devices

Thanks to better AI and machine learning, these wearable *neuro devices* are getting smarter. They can now read brain signals much better. This means they can tell weak signals from noise. Now, we can control computers with our minds. This opens doors in gaming, mental health, and making us more productive.

Institutions like Carnegie Mellon University are key to advancing these gadgets. Their work in the DARPA N3 program is super interesting. They’re exploring ways to use ultrasound and light to make these devices even better.

These gadgets are becoming easier to use, reaching more people. As they mix more with our everyday tech, they’ll change how we monitor health, train our brains, and boost our abilities.

In the end, wearable neuro devices are moving from just an idea to something we can use every day. They’re going to give us new ways to understand our brains. This tech is closing the gap between brain science and practical use.

Neuroprosthetics: Enhancing Human Capabilities

Neuroprosthetics are changing the game for human abilities. They mainly focus on improving how people see, hear, and move. These devices mix cutting-edge materials and smart learning. They give those with disabilities more freedom and a better life.

neuroprosthetics

Restoring Sensory Functions

Sensory restoration has had amazing breakthroughs. Take cochlear implants as an example. By 2019, there were 736,900 people using them around the world. They help people hear by skipping damaged parts of the ear. They then make the hearing nerve active, letting people hear again.

Also, efforts are on to help those who can’t see well. Teams are testing new visual implants that could let people see again. Already, more than 20 teams are seeing good results in early trials. This shows a big promise for the future.

Sensory Device Number of Users Key Advantage
Cochlear Implants 736,900 Restores hearing by stimulating the auditory nerve
Retinal Implants In Phase 1 Trials Potential to restore vision for visually impaired individuals

Improving Motor Functions

Neuroprosthetics are also boosting how people move. Brain-computer interfaces (BCIs) and deep brain stimulation (DBS) are big news. They help people with movement problems or brain disorders like Parkinson’s. DBS sends small electric shocks to the brain and is mainly used for Parkinson’s. It has a low risk of problems from the surgery.

BCIs read brain signals and turn them into actions. They can move robotic arms or control computer pointers. Though they’re slow right now, research is working to make them faster. This could mean big things for how we interact with machines.

People using these devices are really happy with them. This shows they work well. Combining surgery for the nerves, adding new senses, and improving movement is very exciting. It opens new doors in medicine and can change lives. It makes us wonder what we’ll be able to do next.

Sensory Augmentation and Replacement

Neural engineering has brought us exciting sensory augmentation technologies. These include artificial vision devices and hearing implants. They greatly improve the lives of people with sensory impairments. This lets them experience the world in new ways.

sensory augmentation

Artificial Vision

Artificial vision is changing lives by offering new ways to see. The BrainPort device is a great example. It lets blind people distinguish objects with limited vision. It uses a small grid to send signals to the tongue. This creates a kind of visual impression.

Another creative approach is the Forehead Retina System. It changes video into touch sensations on the forehead. This method helps users “see” visual info with touch.

Hearing Implants

Hearing implants are making a big impact worldwide. About 5% of people have severe hearing loss. The Neosensory Buzz wristband uses vibrations to convey sounds. It helps deaf people sense the environment through touch.

Another cool device by Novich and Eagleman changes sound into touch sensations. Worn under the shirt, it helps users feel environmental sounds. Even with fewer motors, these devices effectively compress and transmit sound info.

Device Function Application
BrainPort Tactile visual substitution Visual impairment
Forehead Retina System Convert video stream to touch Visual impairment
Neosensory Buzz Transfer sound through vibrations Hearing impairment
Sound-to-touch device (Novich and Eagleman) Convert sound to touch Hearing impairment

Bi-directional neural links are a huge step forward in neural engineering. They allow two-way interaction between neural devices and the brain. This goes beyond simple one-way talks. It opens the door to more complex systems that could change how humans and machines work together.

In a recent study, researchers used bi-directional BCI to process brain waves with ultrasound. This work involved 25 people. It showed big improvements in BCI communication. People could spell out words like “Carnegie Mellon” using a BCI speller. This shows how focused ultrasound can boost BCI performance.

These advances are key for linking information to and from the brain. A study in Nature Communications found that noninvasive ultrasound can improve EEG-based BCIs. These technologies have exciting possibilities. They could help restore sight and hearing, control robots, and even enable direct communication.

The BRAIN Initiative has funded over 60 projects related to ultrasound. Bin He’s group is noted for making smaller ultrasound devices. These can work better with EEG-based BCIs.

“Damage to the central nervous system affects at least 2 million people per year (Rao and Winter, 2009),” highlighting the urgent need for advanced neural technologies.

Current research on neural links also looks at making them last longer and work better with the body. New materials and designs have helped Multi-electrode arrays (MEAs) last much longer. These advances are crucial. They ensure neuroprosthetic devices and communication aids work well for a long time.

Category Application Example
Neuroprosthetic Systems Restoration Target innervations for bladder control
Neurorepair Systems Rehabilitation Use of intelligent wheelchairs for individuals with locked-in syndrome (LIS)
Neurotherapeutic Systems Pain Management Normal stimulation for pain management

By using both recording and stimulation, bi-directional neural interfaces can change many fields. This includes neuroprosthetics, neurorepair, and pain relief. Experiments already show their potential. For example, they can control wrist movement in monkeys and provide sensory feedback. This hints at a bright future for these advanced neural interfaces.

Integration of Artificial Intelligence and Neural Engineering

Joining AI with neural engineering is changing the game for neural devices. It’s making them smarter in analyzing data and functions. This is especially true for creating better noninvasive brain-computer interfaces (BCIs). AI in this field blends electrical engineering, computer science, biology, and medicine. It aims for complex interactions with the nervous system.

Machine Learning Algorithms

Machine learning is taking neurotechnology to new heights. It lets neural devices be more precise and adaptable. These algorithms handle huge amounts of data. They spot patterns and forecast results that were once impossible to achieve.

  • Enhances diagnostic performance
  • Recommends personalized treatment strategies
  • Enables predictive healthcare
  • Improves robot control and decision-making

Deep Learning Techniques

Deep learning offers strong tools for diving into complex neural data. With layered networks, these methods boost understanding and connection with the nervous system. This means a lot for:

  • Advanced neuroprosthetics to aid individuals with impaired nervous systems
  • Refining BCIs for more seamless thought-to-action controls
  • Optimizing deep brain stimulation (DBS) treatments
Application Impact
Advanced Neuroprosthetics Enhanced sensory and motor function
Brain-Computer Interfaces Improved user control and interaction
Deep Brain Stimulation Effective treatment for Parkinson’s and epilepsy

By adding AI to neural engineering, scientists are breaking new ground. They’re merging neuroscience and tech. This could make neural devices better understand us, work more smoothly, and be more helpful.

Risks and Challenges in Neural Engineering

Neural engineering faces many challenges, from ethical worries to technical hurdles. These challenges not only show the risks in neural engineering. They also show how hard it is to make these technologies safe and work well.

Biomedical Engineering Challenges

One big challenge in biomedical engineering is creating devices that are both precise and reliable. The University of Washington’s BioRobotics Lab is working on brain stimulators to help with motor problems. But, these devices need surgery for battery changes, making the need for better devices clear.

Brain-Computer Interfaces (BCIs) have their own challenges too. They let people with paralysis move prosthetics with their thoughts. Yet, they collect sensitive info about the user’s mind and feelings. This brings up ethical issues about identity, privacy, and who is responsible.

Technical Barriers

Technical obstacles are tough as well. Understanding neural data needs complicated algorithms and lots of computer power. The University of Washington is working on a BCI that lets users control their neurostimulation. This could reduce the surgery needs, showing the difficulty in making devices that users can control.

The long-term care of neural devices is also a big issue. People in these studies need lots of follow-up care and device upkeep. There are ethical problems in making sure people know what they’re signing up for and meeting their long-term needs. With no clear rules on who should take care of these needs after trials, careful planning is essential. Researchers, funders, and makers all need to think this through.

Ethical and Societal Implications

Neural engineering is transforming medicine and tech. It’s key to look into its ethical and societal effects. Ensuring equitable development needs focus on ethics and regulations.

Privacy Concerns

Privacy is a big worry with neural tech like BCIs. They handle sensitive info, risking data breaches. Questions about who owns and can use this data arise.

To protect neural data, strong policies are needed. Tight rules can keep personal info safe from misuse and unauthorized access.

Regulatory Considerations

Neural tech’s fast growth demands strict regulations for ethics and safety. Agencies like the FDA play a key role in this.

Regulations should cover device approval, monitoring, and checking for side effects. We must ensure innovation is safe and privacy is protected, benefiting everyone fairly.

Also, inclusivity in research is crucial. It’s important to fix the lack of diversity, like the low numbers of Black scientists in biomedicine.

By focusing on these rules, we can support neural engineering’s ethical advance. It ensures people’s well-being and privacy are safeguarded.

Future Possibilities in Neural Engineering

The future of neural engineering holds great promise. It features emerging tech that could lead to breakthroughs in medicine and technology. Researchers are working on new interfaces and treatments. They aim to close the gap between humans and machines.

Emerging Technologies

Companies like Neuralink, Kernel, and Galvani Bioelectronics are at the forefront. They’re improving brain repair and brain-machine interfaces (BMIs). This is key as Europe faces a high rate of neurological disorders.

Meanwhile, Medtronic and Boston Scientific Neuromodulation Corp. focus on treatments for epilepsy, Parkinson’s disease, chronic pain, and stroke. These developments are hopeful for managing conditions like dementia and migraine.

Potential Breakthroughs

About 200,000 people globally have neurotechnology in their brains. These devices could enhance cognition, manage disabilities, and treat chronic pain. Neuralink, for example, plans to significantly expand its team.

The U.S. leads in brain stimulation patents. This highlights its key role in upcoming advancements. The purchase of CTRL-labs by Facebook in 2019 shows the growing interest from big tech companies.

Here’s a brief look at the main players and their focus in the neural engineering field:

Company Focus Area
Medtronic Neuropathy Devices
Boston Scientific Neuromodulation Corp. Devices for Epilepsy and Chronic Pain
Neuralink Brain-Machine Interfaces
Kernel Brain Repair Technologies
Galvani Bioelectronics Neurological Disorder Solutions
CTRL-labs Neural Interfaces

The neural engineering field is just starting but has huge potential for growth and innovation. Exciting technology is on the horizon. It promises to blend humans and machines in groundbreaking ways.

Neural Engineering in Everyday Life

Neural engineering brings exciting changes to our daily lives, making things easier and more inclusive. It’s growing fast, introducing useful tools for everyday use and helping people access new technologies.

Consumer Applications

Neural tech is becoming a part of our daily lives with many cool uses. It helps connect our thoughts directly with machines. For example, brain-computer interfaces let us control gadgets or smart homes just by thinking about it. This shows how well neural engineering is blending into our everyday items.

Accessibility Enhancements

For people with disabilities, neural engineering is a game-changer. It brings life-changing tools like cochlear implants and advanced limb replacements. Also, new ultrasound uses are helping fight brain cancer and other serious diseases. As these technologies advance, they promise a more inclusive world for everyone.

Research Area Focus
Sensory Physiology Studies on neural circuits and cerebral cortex processing
Neuroprosthetics Development of cochlear and vestibular implants
Therapeutic Ultrasound Applications addressing brain cancer and CNS diseases
Digital Signal Processing Enhancement for speech and audio systems for the hearing impaired

Conclusion

Neural engineering links technology with neuroscience. It offers new ways to understand how our brains work and to improve health treatments. By using computers and math, it can manage big data from the brain’s complex activities. This summary shows how the field can change lives by finding problems in cells or helping paralyzed people interact with the world.

It has big potential for diseases like amyotrophic lateral sclerosis (ALS), where many neurons are lost before we even notice symptoms. Also, techniques like subdural electrode recordings make it easier and safer to pick up brain signals. This could help treat many conditions more accurately.

The future of neurotechnology looks bright, thanks to major conferences that help the field grow. Since the first International IEEE EMBS Neural Engineering Conference in 2003, there’s been a lot of progress and collaboration. These meetings bring together experts to share ideas, leading to breakthroughs that combine neural science with Artificial Intelligence. Neural engineering might soon change medicine, boost human abilities, and deepen our brain knowledge.

FAQ

What is neural engineering?

Neural engineering is where neuroscience meets engineering. It’s about making technologies that help and learn more about how our brains work. These technologies use ideas from biology, computer science, and electrical engineering.

They aim to understand, fix, and enhance brain functions. This includes helping people with neurological issues.

What is neural coding?

Neural coding is about how brain cells communicate. It’s key in neural engineering. Understanding it helps researchers know how our brains interpret the world around us.

What are brain-computer interfaces (BCIs)?

BCIs let the brain talk directly to machines. They turn thoughts into actions without moving. This means you can control computers or prosthetics just by thinking.

What are the differences between noninvasive, invasive, and minimally invasive BCIs?

Noninvasive BCIs don’t enter the body. They use sensors on your skin to read brain activity. Invasive BCIs are put right into the brain for clearer signals.

Minimally invasive BCIs are a halfway option. They’re less intense than full surgery.

How does Deep Brain Stimulation (DBS) work?

DBS puts tiny electrodes in the brain. These electrodes stimulate certain areas. This helps manage conditions like Parkinson’s by adjusting how brain cells talk to each other.

What is Transcranial Focused Ultrasound (tFUS)?

tFUS uses sound waves to safely change brain activity. It’s a new way to treat brain disorders without surgery. It shows promise for noninvasive treatment.

What are some medical applications of neural engineering?

Neural engineering tackles neurological issues with DBS and new diagnostics like detailed brain scans. It also helps in rehabilitation using neural interfaces.

What are wearable neural devices?

Wearable devices like EEG headsets track how your brain works in real time. They make it easy to monitor your brain health every day.

What are neuroprosthetics?

Neuroprosthetics help people with disabilities regain or improve their senses and movement. They use new materials and learning algorithms to boost independence and life quality.

How is artificial vision used in neural engineering?

Artificial vision helps people who can’t see well. It creates a way for them to “see” using technology. This helps them interact better with their surroundings.

What role does AI play in neural engineering?

AI improves neural devices by making them smarter and more adaptable. It works on analyzing data better. This helps noninvasive BCIs and other tech to be more effective.

What are some challenges faced in neural engineering?

Challenges include ethical worries and understanding complex brain data. There’s also the need to make devices very precise. Plus, we must think about safety and the long-term impact of these devices.

What ethical and societal concerns are associated with neural engineering?

There are concerns about privacy and how neural data is used. It’s important to have strong rules to protect people and use the tech ethically.

What future possibilities exist for neural engineering?

The future holds exciting tech that could lead to big discoveries in health and tech. More research will bring about advanced devices and treatments.

How is neural engineering impacting everyday life?

Neural engineering is making its way into our daily lives through apps and accessibility tools. It offers better experiences with BCIs and helps people with disabilities greatly.

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