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Methods of reversing oxidative stress with lactulose and other prebiotic compounds
Patent published on the 2025-03-06 in WO under Ref WO2025049896 by PREBIOTIC HEALTH SCIENCES INC [US] (Kohn Kenneth I [us], Kohn Armand S [us])
Abstract: A composition for reversing oxidative stress including a gut flora maintaining agent. A food product for reversing oxidative stress including a gut flora maintaining agent. A method of reversing oxidative stress, by administering the gut flora maintaining agent to an individual, inducing the individual's microbiome to generate systemic hydrogen, and reversing oxidative stress.[...]
Our summary: Reversing oxidative stress with lactulose and prebiotic compounds, composition and food product including gut flora maintaining agent, method of inducing microbiome to generate systemic hydrogen.
oxidative stress, lactulose, prebiotic compounds, gut flora
Patent
Anaerostipes sp. and bacteroides uniformis prebiotic composition and method of use
Patent published on the 2025-03-06 in WO under Ref WO2025049238 by PURDUE RES FOUNDATION [US] (Hamaker Bruce R [us], Cantu Jungles Thaisa M [us])
Abstract: A prebiotic fiber composition obtained from Gloeoporus thelephoroides, Ganoderma lucidum, Pholiota nameko, and/or Pleurotus pulmonarius; and a method of promoting growth of Anaerostipes sp., Bacteroides uniformis, or both in the gut microbiome of an animal, which method comprises orally administering the prebiotic fiber composition, alone or in further combination with live Anaerostipes sp., Bacteroides uniformis, or both, simultaneously or sequentially.[...]
Our summary: Method of promoting growth of specific gut microbiome bacteria using prebiotic fiber composition obtained from various mushrooms and administering live bacteria.
prebiotic, composition, Anaerostipes sp., Bacteroides uniformis
Patent
Computational exploration of the global microbiome for antibiotic discovery
Patent published on the 2025-03-06 in WO under Ref WO2025050118 by FUDAN UNIV [CN] (De La Fuente-nunez CÉsar [us], Der Torossian Torres Marcelo [us], Pedro Fragao Bento Coelho Luis [lu], Dias Santos JÚnior CÉlio [br])
Abstract: Novel antibiotics are needed to combat the antibiotic-resistance crisis. Presented herein are machine learning-based approaches for predicting antimicrobial peptides (AMPs) within the global microbiome and leverage a vast dataset that can include metagenomes and prokaryotic genomes from environmental and host-associated habitats to create a comprehensive catalog comprising distinct, non-redundant peptides, the majority of which are novel. This platform provides insights into the evolutionary ori[...]
Our summary: Computational exploration of global microbiome for antibiotic discovery using machine learning to predict antimicrobial peptides from metagenomes and prokaryotic genomes, validating predictions with synthesized peptides tested against drug-resistant pathogens and human gut commensals.
machine learning, antimicrobial peptides, metagenomes, antibiotic discovery
Patent
Bacteroides eggerthii kgmb05336 strain and use thereof
Patent published on the 2025-03-06 in WO under Ref WO2025048282 by AJOU UNIV INDUSTRY ACADEMIC COOPERATION FOUNDATION [KR] (Kim Soon Sun [kr], Eun Jung Woo [kr], Cheong Jae Youn [kr], Cho Hyo Jung [kr], Yoon Moon Gyeong [kr], Weon Ji Hyang [kr], Lee Jung-sook [kr])
Abstract: The present invention relates to a Bacteroides eggerthii KGMB05336 strain and a use thereof. Through the analysis of the microbiome in patients with non-alcoholic fatty liver disease that is caused by obesity, the Bacteroides eggerthii strain was identified as a significant strain. Oral administration of the Bacteroides eggerthii strain to animal models of obesity and non-alcoholic fatty liver disease caused by obesity resulted in body weight reduction, liver weight reduction, decrease of fat ac[...]
Our summary: Bacteroides eggerthii KGMB05336 strain identified in microbiome analysis of patients with non-alcoholic fatty liver disease caused by obesity. Oral administration to animal models resulted in significant improvements in weight, fat accumulation, and serum levels, suggesting potential for prevention and treatment of obesity-related diseases.
Bacteroides eggerthii, strain, microbiome, obesity
Patent
Biometric monitoring and treatment device
Patent published on the 2025-03-06 in WO under Ref WO2025050121 by ACTIVE4D INC [US] (D'lima Darryl [us], Hoenecke Heinz [us])
Abstract: Typically, the human joints and muscles are complex regions of the body that have to satisfy several demands such as mobility, stability, and strength. Therefore, capturing these subtleties requires advanced techniques. Accordingly, a biometric device, comprising; an adhesive patch; a power supply; an electrode array with one or more sensor elements configured to measure electrical signals generated by one or more muscles; and a machine controller communicatively coupled to the electrode array c[...]
Our summary: Complex human joints and muscles demand advanced techniques for monitoring and treatment using a biometric device with an electrode array and machine controller to assess health conditions and provide feedback.
Biometric monitoring, treatment device, electrode array, machine controller
Patent
A consciousness disorder evaluation robot and an evaluation method integrating multi-modal biometric characteristics
Patent published on the 2025-02-24 in NL under Ref NL2039499 by UNIV BEIJING SCIENCE & TECHNOLOGY [CN] (Hongzhen Cui [cn], Longhao Zhang [cn], Yunfeng Peng [cn], Xingyu Li [cn], Shichao Wang [cn])
Abstract: A Consciousness Disorder Evaluation Robot and An Evaluation Method Integrating Multi-modal Biometric Characteristics The invention provides a consciousness disorder evaluation robot and an evaluation method integrating multi-modal biometric characteristics. The GCS scoring process is embedded into the multi—modal consciousness disorder evaluation algorithm, and the consciousness evaluation task of the wounded can be better realized without the 10 participation of medical professionals. Intelli[...]
Our summary: A consciousness disorder evaluation robot and evaluation method integrating multi-modal biometric characteristics. GCS scoring process embedded into algorithm for better realization of consciousness evaluation task. Intelligent algorithm assisted decision making ensures efficiency and reduces human subjective factors.
evaluation, robot, multi-modal biometric, algorithm
Patent
Interesting read, but arent patents potentially harmful to biodiversity by monopolizing access to genetic resources? Thoughts?
Interesting article, but are we doing enough to patent indigenous knowledge? Its high time we protect them too, right?
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