Latest Publications & Patents on Biomaterials
This is our latest selection of worldwide publications and patents in english on Biomaterials, between many scientific online journals, classified and focused on biomaterial, tissue engineering, biodegradability, biopolymer, biocompatibility, scaffold, biodegradable, hydroxyapatite, chitosan and alginate.
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Chrome Doped Hydroxyapatite Enriched with Amoxicillin Layers for Biomedical Applications
Published on 2025-02-15 by Carmen Steluta Ciobanu, Daniela Predoi, Simona Liliana Iconaru, Krzysztof Rokosz, Steinar Raaen, Catalin Constantin Negrila, Liliana Ghegoiu, Coralia Bleotu, Mihai Valentin Predoi @MDPI
Abstract: In the last decade, it has been observed that the field of biomaterials has gained the attention of the researchers. This study presents the physicochemical and biological properties of coatings based on chromium-doped hydroxyapatite (CrHAp) and chromium-doped hydroxyapatite enriched with amoxicillin (CrHApAx). The coatings were obtained for the first time using the dip coating technique, beginning from dense suspensions of CrHAp and CrHApAx. The obtained layers were then analyzed by various met[...]
Our summary: Physicochemical and biological properties of Chrome Doped Hydroxyapatite enriched with Amoxicillin layers were studied. The coatings showed good stability, biocompatibility, and potential antibacterial activity against Pseudomonas aeruginosa.
Hydroxyapatite, Amoxicillin, Biomedical Applications, Dip Coating
Publication
Experimental Study Regarding the Synthesis of Iron Oxide Nanoparticles by Laser Pyrolysis Using Ethanol as Sensitizer; Morpho-Structural Alterations Using Thermal Treatments on the Synthesized Nanoparticles
Published on 2025-02-15 by Florian Dumitrache, Anca Criveanu, Iulia Lungu, Claudiu Fleaca, Lavinia Gavrila-Florescu, Iuliana Morjan, Ioan Stamatin, Adriana Balan, Vlad Socoliuc, Bogdan Vasile @MDPI
Abstract: The laser pyrolysis technique was used in the synthesis of magnetic iron oxide nanopowders in the presence of ethanol vapors as a sensitizer. This technique uses the energy from a continuous-wave CO2 laser operating at a 9.25 μm wavelength, which is transferred to the reactive precursors via the excited ethanol molecules, inducing a rapid heating of the argon-entrained Fe(CO)5 vapors in the presence of oxygen. For a parametric study, different samples were prepared by changing the per[...]
Our summary: Experimental study on the synthesis of iron oxide nanoparticles using laser pyrolysis with ethanol as a sensitizer. Morpho-structural alterations observed in nanoparticles after thermal treatments. Investigation of crystallinity, magnetic properties, and stability of the synthesized nanoparticles.
Iron Oxide Nanoparticles, Laser Pyrolysis, Ethanol Sensitizer, Morpho-Structural Alterations
Publication
Investigation of the Antibacterial Activity of ZnO-Loaded Alginate/Hyaluronic Acid Aerogels for Wound Dressing Applications
Published on 2025-02-15 by Tamara Athamneh, Alaa Abuawad, Tasneem Odat, Areen Alshweiat, Rana Obaidat, Farah Bani Yaseen, Mohammad A. Al-Najjar, Raghad Garafat, Razan Altarabeen, Irina Smirnova, Pavel Gurikov @MDPI
Abstract: The prevalence of bacterial infections in wounds is a significant challenge to successful wound healing. This study investigates the antibacterial effect of hyaluronic acid and alginate aerogel loaded with zinc oxide nanoparticles as a potential dressing for wound healing. The aerogel composite was synthesized via supercritical gel drying and characterized by scanning electron microscope, Fourier transform infrared spectroscopy, and nitrogen porosimetry. The absorptivity of the prepared aerogel [...]
Our summary: Investigation of antibacterial activity of ZnO-loaded alginate/hyaluronic acid aerogels for wound dressing applications. Prevalence of bacterial infections in wounds is a challenge. Study explores antibacterial effect of aerogel loaded with zinc oxide nanoparticles for wound healing. Aerogel characterized and evaluated for antibacterial activity and water absorption.
ZnO nanoparticles, Alginate, Hyaluronic acid, Aerogels
Publication
Assessment of the Influence of Antisolvent 3D Printing Conditions on the Mechanical and Biological Properties of Poly(lactic-co-glycolic) Acid Scaffolds
Published on 2025-02-14 by Anton V. Mironov, Ekaterina M. Trifanova, Tatyana B. Bukharova, Andrey V. Vasilyev, Viktoria O. Chernomyrdina, Irina A. Nedorubova, Valeriya S. Kuznetsova, Andrey G. Dunaev, Vladimir K. Popov, Anatoly A. Kulakov, Fedor F. Losev, Dmitry V. Goldshtein @MDPI
Abstract: This paper describes an evaluation of the mechanical and biological properties of highly porous, biocompatible poly(lactic-co-glycolic acid) (PLGA) scaffolds produced using the antisolvent 3D printing technique under various forming conditions. The dependence of the scaffolds’ microstructure, PLGA molecular weight distribution, and cell adhesion properties on temperature and injection nozzle diameter was evaluated. All samples consisted of fibers with different inner polymer distri[...]
Our summary: Evaluation of PLGA scaffolds produced using antisolvent 3D printing technique under various forming conditions, assessing microstructure, molecular weight distribution, and cell adhesion properties. Temperature and injection nozzle diameter were found to influence scaffold characteristics, with different effects on compression load and elasticity.
Antisolvent 3D Printing, Mechanical Properties, Biological Properties, PLGA Scaffolds
Publication
Balancing Conductivity and Morphology in Aniline-Tuned Biopolymer–Starch Composites
Published on 2025-02-14 by Mohammed E. Ali Mohsin, Suleiman Mousa @MDPI
Abstract: This work investigates the optimization of aniline content in polyaniline (PANI)/sago starch blends prepared via in situ oxidative polymerization under ultrasonic irradiation. Building upon our previous optimizations of pH and sonication time, this study focuses on the effect of aniline concentration (5–65 wt%) on electrical conductivity, morphological dispersion, and thermal stability. Various characterization techniques, including field emission scanning electron microscopy (FE-S[...]
Our summary: This study explores the impact of aniline content on the conductivity and morphology of PANI/sago starch composites. Results show that an aniline loading of around 35 wt% achieves the best balance between conductivity and structural integrity, offering potential for high-performance biopolymer-based conductors.
aniline content, conductivity, morphology, optimization
Publication
Light-Intensity-Dependent Control of Collagen Hydrogel Properties via Riboflavin Phosphate-Mediated Photocrosslinking
Published on 2025-02-14 by Seungyeop Yoo, Won-Gun Koh, Hyun Jong Lee @MDPI
Abstract: While photocrosslinked collagen hydrogels show promise in tissue engineering, conventional approaches for property control often require complex chemical modifications or concentration changes that alter their biochemical composition. Here, we present the first systematic investigation of light-intensity-dependent control in riboflavin phosphate (RFP)-mediated photocrosslinking as a novel, single-parameter approach to modulate hydrogel properties while preserving native biochemical environments.[...]
Our summary: Light-intensity-dependent control of collagen hydrogel properties via riboflavin phosphate-mediated photocrosslinking allows for precise modulation of hydrogel properties while preserving native biochemical environments. Varying light intensities during hydrogel fabrication results in unprecedented control over network architecture, mechanical performance optimization, and enhanced cell proliferation in both 2D and 3D environments.
Photocrosslinking, Collagen Hydrogel, Riboflavin Phosphate, Light Intensity
Publication
Cylindrical composite nerve scaffold, and preparation method thereof and use thereof
Patent published on the 2025-01-31 in LU under Ref LU507924 by SHANGHAI SIXTH PEOPLES HOSPITAL [CN] (Fan Cunyi [cn], Wang Xu [cn], Qian Yun [cn])
Abstract: The invention discloses a cylindrical composite nerve scaffold and a preparation method and application thereof, belonging to the technical field of medical biomaterials. The preparation method of the cylindrical composite nerve scaffold includes the following steps: preparing a bio-responsive degradable material film and an extracellular matrix-like composite hydrogel and covering the bio-responsive degradable material film on the outer surface of the extracellular matrix-like hydrogel to obtai[...]
Our summary: Preparation of cylindrical nerve scaffold, FDA certified materials, natural extracellular matrix, nerve regeneration guidance
nerve scaffold, preparation method, biomaterials, biocompatibility
Patent
Plasticizer-free biodegradable composition processable into an end product by 3d printing
Patent published on the 2025-01-30 in RO under Ref RO138585 by INSTITUTUL NAT DE CERCETARE DEZVOLTARE PENTRU CHIMIE SI PETROCHIMIE ICECHIM [RO] (Dimonie Doina Olga Afina [ro], Oancea Florin [ro], Toma Ion [ro], Ladaniuc Magdalena- Adriana [ro], Gabor Augusta Raluca [ro], Nicolae Cristian Andi [ro], RĂdiŢoiu Valentin [ro], Raduly Florentina Monica [ro], TricĂ Bogdan [ro])
Abstract: The invention relates to a biodegradable composition free of liquid plasticizers for making products with a durability higher than two years by 3D printing. According to the invention, the composition consists of 20...200 parts of corn starch consisting of 30% amylose and 70% amylopectin, which is melt-compounded with 20...110 parts of poly epsilon caprolactone (PLC) with a molecular weight ranging between 100000...120000 g/mol. (160°C with 2.16 kg), with 0...150 parts of polylactic acid (PLA) [...]
Our summary: Biodegradable composition processable into end product by 3D printing, durability higher than two years, corn starch and poly epsilon caprolactone melt-compounded, inorganic filling and thermal stabilizers included.
3D printing, biodegradable composition, plasticizer-free, corn starch
Patent
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