This is our latest selection of worldwide publications and patents in english on Biomaterials, between many scientific online journals, classified and focused on biomaterial, tissue engineering, biodegradability, biopolymer, biocompatibility, scaffold, biodegradable, hydroxyapatite, chitosan and alginate.
Rational Design Using Artificial Intelligence Tools
Published on 2025-07-11 by Carlos Illanes-Bordom�s, Mariana Landin, Carlos A. Garc�a-Gonz�lez @MDPI
Abstract: This study explores novel alginate–konjac glucomannan core–shell aerogel particles for drug delivery systems fabricated via air-assisted coaxial prilling. A systematic approach is needed for the optimization of this method due to the numerous processing variables involved. This study investigated the influence of six variables: alginate and konjac glucomannan concentrations, compressed airflow, liquid pump pressures, and nozzle configuration. A hybrid software using A[...]
Our summary: This study utilizes Artificial Intelligence tools to optimize the fabrication of alginate-konjac glucomannan core-shell aerogel particles for drug delivery systems. The process involves investigating six variables and using a hybrid software to achieve a 100% desirable solution. The resulting aerogels exhibit high specific surface area and are capable of releasing drugs effectively.
Artificial Intelligence, Drug Delivery Systems, Optimization, Aerogel
Publication
Study on the Adsorption Behavior of a Cellulose Nanofibril/Tannic Acid/Polyvinyl Alcohol Aerogel for Cu(II), Cd(II), and Pb(II) Heavy Metal Ions
Published on 2025-07-09 by Xuejin Zhang, Yulong Tian, Huanhuan Chen, Ying Liu, Shuaichuang Han, Minmin Chang, Jingshun Zhuang, Qingzhi Ma @MDPI
Abstract: Nanocellulose-based composite aerogels have the advantages of high porosity, biodegradability, and biocompatibility, with wide applications in many fields, such as adsorption, separation, energy storage, and heat insulation. In this study, a nanocellulose-based composite aerogel (NCA) was prepared using the one-pot method with cellulose nanofibrils (CNFs), tannic acid (TA), and polyvinyl alcohol (PVA) as raw materials. The adsorption behaviors of Pb2+, Cd2+, and Cu2+ were also studied. FT-IR ana[...]
Our summary: Study on the adsorption behavior of a nanocellulose-based composite aerogel for Cu(II), Cd(II), and Pb(II) heavy metal ions. High porosity, biodegradability, and biocompatibility make nanocellulose-based composite aerogels versatile in various applications. The study prepared a nanocellulose-based composite aerogel using cellulose nanofibrils, tannic acid, and polyvinyl alcohol, showing excellent adsorption capacity for heavy metal ions.
nanocellulose, composite aerogel, adsorption behavior, heavy metal ions
Publication
Bionic Bovine Achilles Tendon Collagen Composite Membrane Loaded with Anti-Inflammatory Kukoamine B Promotes Skin Wound Healing
Published on 2025-07-04 by Ruting Luo, Yujie Mu, Le Zhao, Jinglin Hua, Lixin Cao, Danting Chen, Kun Li, Zhenkai Jin, Yanchuan Guo, Bing Zhang, Min Wang @MDPI
Abstract: Skin is the first line of defence between the human body and the outside world, and it is constantly exposed to external injuries and wounds for a variety of reasons. Collagen is a structural protein of the extracellular matrix and an important component of the dermis. As a wound dressing, collagen not only provides nutrients to wounds but also enhances the immune response in the pre-healing phase, making it an excellent biomaterial for healing. In this study, we used electrospinning and freeze-[...]
Our summary: Bovine Achilles Tendon Collagen Composite Membrane loaded with Anti-Inflammatory Kukoamine B promotes skin wound healing through enhanced immune response and nutrient delivery, making it an excellent biomaterial for healing. The physicochemical properties and biocompatibility of the membrane were verified, showing significant effects on skin wound healing in a mouse model. The composite membrane had the best capacity for promoting wound healing and can be used as a wound dressing for further research and development.
Collagen, Electrospinning, Anti-Inflammatory, Wound Healing
Publication
Geopolymer-based concrete composition
Patent published on the 2025-06-26 in WO under Ref WO2025137733 by PLANTAER INC [US] (Abdallah Robert Joseph [us], Ruiz Manuel Jesus Benitez [us])
Abstract: Embodiments provide a novel concrete composition and method for forming a geopolymer-based building material. The composition comprises a geopolymer binder, water-retentive aggregates with long-term water retention properties and biological surface growth facilitation, where at least one aggregate is cellulose pre-treated with a saturating coating solution. The composition also includes rigid, porous aeration aggregates and strength aggregates. The method involves mixing these components to form[...]
Our summary: Novel geopolymer-based concrete composition with water-retentive aggregates, cellulose pre-treated aggregates, and aeration aggregates. Method involves mixing components to form pourable material, then curing under controlled conditions. Construction material includes aluminosilicate precursor, biopolymer-coated aggregates, and porosity agent for enhanced sustainability and durability.
geopolymer, concrete composition, building material, construction material
Patent
Composite rotator cuff patch and preparation method therefor
Patent published on the 2025-06-12 in WO under Ref WO2025118346 by GUANHAO BIOTECH CO LTD [CN] (Mo Ziru [cn])
Abstract: Disclosed in the present application are a composite rotator cuff patch and a preparation method therefor. The composite rotator cuff patch is divided into an electrospun layer and a collagen layer. An electrospun nanofiber membrane is coated with a layer of cross-linked collagen gel, and then composite freeze-drying is carried out to obtain the composite rotator cuff patch of the present application. The rotator cuff patch has good biocompatibility and proper tissue adhesion, does not require s[...]
Our summary: Composite rotator cuff patch with electrospun and collagen layers, prepared by composite freeze-drying for good biocompatibility and tissue adhesion, no sutures needed for fixation, degrades in vivo without postoperative removal.
composite, rotator cuff, patch, preparation
Patent
Injectable hydrogel for sustained co-delivery of an antigen and an adjuvant, and uses thereof
Patent published on the 2025-03-13 in WO under Ref WO2025054360 by THE REGENTS OF THE UNIV OF CALIFORNIA [US] (Wang Szu-wen [us], Wang Lu [us], Davies David Huw [us], Ramirez Aaron [us])
Abstract: The disclosure provides for a vaccine depot formulation that comprises a biodegradable thermosensitive hydrogel that has been loaded or embedded with nanoparticles that comprise an antigen and adjuvant, and uses thereof for protecting a subject from an infection or disease.[...]
Our summary: Injectable hydrogel for sustained co-delivery of antigen and adjuvant, protection from infection or disease, biodegradable thermosensitive hydrogel.
hydrogel, sustained release, co-delivery, vaccine depot
Patent
Characterization and Modelling of Biomimetic Bone Through Additive Manufacturing
Published on 2025-03-10 by Niranjan Srinivasan, Mohsen Barmouz, Bahman Azarhoushang @MDPI
Abstract: The long-term success of bone implant scaffolds depends on numerous factors, such as their porosity, mechanical properties, and biocompatibility. These properties depend on the type of material, such as metals and their alloys or ceramics, and the procedure used to create the scaffolds. This study aims to find the biomimetic properties of aluminum 6061 (Al 6061) alloy through Digital Light Processing (DLP) and sintering. Hollow cylindrical Al 6061 samples are printed through the DLP process at 9[...]
Our summary: Long-term success of bone implant scaffolds depends on porosity, mechanical properties, and biocompatibility. Study aims to find biomimetic properties of Al 6061 alloy through DLP and sintering. Scaffold model created with anisotropic properties closer to trabecular bone.
Additive Manufacturing, Biomimetic Bone, Characterization, Modelling
Publication
Anode assembly comprising solid electrolyte layer directly coated on anode layer and all solid state battery comprising same
Patent published on the 2025-03-06 in WO under Ref WO2025049364 by FACTORIAL INC [US] (Hao Fang [us], Wakaba Daniel [us], Kim Hyun Seok [us], Nguyen Minh [us], Burdynska Joanna [us])
Abstract: Disclosed is an anode assembly comprising an anode layer and a solid electrolyte layer prepared by directly coating a slurry comprising a solid electrolyte and a binder on the anode layer. The interfacial resistance between the anode layer and the solid electrolyte membrane is lower than that of an assembly prepared without direct coating. In one embodiment, the solid electrolyte is a sulfide electrolyte. In one embodiment, the binder is a nonfibrillizable binder. In one embodiment, the electrol[...]
Our summary: Anode assembly with solid electrolyte layer directly coated on anode layer, lower interfacial resistance, sulfide electrolyte without scaffold layer.
solid electrolyte layer, anode layer, anode assembly, all solid state battery
Patent
